Written By Torie Robinson

How Might The Ketogenic Diet Alter Epileptic Seizures? - Stefanie Prast-Nielsen, Karolinska Institutet, Sweden

Podcast:

We hear about Stefanie’s clinical study involving fecal samples from a group of children with refractory epilepsy who started the ketogenic diet; investigating their gut microbiota and how it may be related to changes in epileptic seizures.
Stefanie also speaks of future international collaborations in collections of stool samples for furthering this epilepsy research.

Clinicians: you have any questions for Stefanie or would like to contact her to discuss collaboration in her new study, please connect with her via the links below.

Families: If you’d like to be involved in the study, please contact your neurologist.

This is part 2 of 2.

    • Intro

    • Study into impact of ketogenic diet on microbiota

    • What is the ketogenic diet?

    • Correlation vs causation

    • Cohort: number of people involved in study and what’s needed in next

    • Type of patients in study

    • Follow-up study

    • International patient participation

    • Confidence speaking about feces

    • Clinician & patient involvement outreach

    • Stool collection & analysis

    • Pre-existing identification of correlation between microbiota, feces, and seizures - by carers

    • Benefits of epilepsy research to society

    • Conclusion

  • Stefanie is an Assistant Professor in Metagenomics and Research Specialist in Multiomics, Machine Learning and Data Integration at the Centre for Translational Microbiome Research (CTMR), MTC, Karolinska Institutet.

    Stephanie has a PhD in Medical Biochemistry from the Department of Medical Biochemistry and Biophysics (MBB), Karolinska Institutet and spent several years as a Postdoc in Bioinformatics at both the Department of Cell and Molecular Biology (CMB) and Karolinska University Hospital. She joined the Centre for Translational Microbiome Research in 2017 where she has been Assistant Professor over the last four years. Her main research activities focus on the gut microbiota in various diseases with emphasis on dietary interventions and the microbiota-gut-brain axis.

  • Email: stefanie.prast-nielsen@ki.se

    Twitter: NielsPrast 

    LinkedIn: linkedin.com/in/stefanie-prast-nielsen 

    University: Karolinska Institutet

    Original papers: Nature | PubMed

 
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Torie Robinson
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