Graphene Tech: Accessing & Recording Brain Activity Where EEG Electrodes Can't - Rob Wykes, UCL & University of Manchester, UK
Podcast:
Hear how graphene technology can access and record abnormal brain activity where EEG electrodes can't! With epilepsy researcher Rob Wykes: from both UCL Hospital for Neurology & Manchester University!
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Rob & how he started his work
Graphene technology research
How graphene works
Use of the technology for epilepsy surgery
How invasive are the probes?
Use of microscope with pre-clinical models
Next steps: clinical development – MRI compatible
Negative impact of political change upon epilepsy research
How to learn more
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Rob leads 2 epilepsy research labs: one at the UCL Queen Square Institute of Neurology & Neurosurgery, and one at the University of Manchester, UK.
His research focuses on Paroxysmal CNS disorders with a particular focus on epilepsy, and can be broadly broken down into 2 research categories:
1. Gene therapy approaches to treat drug-refractory forms of epilepsy.
2. Development and application of novel imaging and electrophysiological approaches to detect seizure activity and spreading depolarisations in preclinical models of epilepsy, migraine, glioblastoma and stroke. A recent focus is application of implantable Graphene-based transistor arrays to map pathological brain activity.
Rob’s labs at UCL and Manchester utilise implanted graphene based technologies (transistor arrays and stimulating electrodes) to gain a better understanding of neurological disease pathology and to offer novel therapeutic options. He continues to work on gene therapy approaches for CNS disorders.
Rob’s Ph.D. was “Calmodulin regulation of calcium channels and neurotransmitter release in bovine adrenal chromaffin cells” in the department of Cell Physiology and Pharmacology at the University of Leicester under the supervision of Dr Liz Seward and subsequently characterised TRP channel and P2X receptor expression in human lung mast cells.
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Other episodes:
Helplines, email address, and website for Ukrainians seeking Anti-Seizure Medications.