Brain Tissue For Epilepsy Research - Neuropathology! - Katja Kobow, Kobow Lab, Universitätsklinikum Erlangen, Germany
Podcast:
Award-winning molecular neuropathologist & PI Katja Kobow explains her research into unraveling the intricate interplay between epigenetic alterations and the development of epilepsy, specifically in the context of the adult post-mitotic brain.
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Katja intro
What is neuropathology?
Obtaining and using brain tissue
Research into epigenetic mechanisms in drug-resistant epilepsy
Causes of epilepsy and epigenetics as a marker
Identifying cell abnormalities through DNA methylation!
Informing clinician of patient histological/structural abnormalities
Not reporting epigenetic markers to influence clinical decision-making, yet
Promising results from molecular diagnostic biomarkers - blood as well as brain
Excited but not doing a Theranos!
Managing people's dreams about ultra-complex epigenetics
Current foci: diagnostic and patient stratification aspects
Educating the wider public re epilepsy research - money and exciting
Check out kobowlab.org
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Katja Kobow is PI of the Kobow Lab at the Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany. A biochemist turned molecular neuropathologist with a Ph.D. in neuroscience and genetics, her independent research focuses on epigenetics and focal epilepsies where she works to improve understanding of the brain’s mechanisms and the diagnoses of samples.
Researching a disease like epilepsy allows her to study the human brain’s complexity and beauty while finding meaning in improving patients’ lives and clinical care.
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Twitter: KatjaKobow
Website: kobowlab.org
ILAE: Michael Prize winner 2021
University: Neuropathologisches Institut
Papers: Orcid
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