Injecting MicroRNA To Help Dogs & Humans with Epilepsy - David Henshall, RCSI, FutureNeuro, Republic of Ireland
Podcast:
Hear of the new miRNA treatment for epilepsy being used in dogs and hopefully in the future, humans - with molecular physiologist and neuroscientist, David Henshall. This is episode 1 of 2.
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New study with pet dogs
What happens in the dog trial
Measuring trial safety & effectiveness
How the treatment was identified
What are microRNAs?
A short-term tinkering!
How long does the treatment last
Working with and benefiting dogs
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David’s undergraduate degree was from the University of Bristol, graduating with First Class Honours in Pharmacology in 1994. Postgraduate training on stroke modelling and neuronal injury was under Drs John Sharkey and Steve Butcher in the Department of Pharmacology and the Fujisawa Institute for Neuroscience at the University of Edinburgh, leading to the award of a Ph.D. in Neuropharmacology in 1997. Post-doctoral training in cell death signaling in epilepsy was under Prof Roger Simon at the Department of Neurology, University of Pittsburgh, USA. Following NIH funding in 1999, David was appointed Assistant Scientist at the newly established Robert S. Dow Neurobiology Laboratories, a private non-profit research institute in Portland, Oregon, USA. An RO1 award for research on apoptosis signaling in epilepsy established an expanded research team and in 2003, promotion to Associate Scientist. In early 2004, David moved to RCSI as Senior Lecturer in Molecular Physiology & Neuroscience. David has authored over 195 papers and 10 book chapters. He is the Chair of the International League Against Epilepsy Neurobiology Commission''s Task Force on Genetics/Epigenetics and a Benchmark Steward for the National Institutes of Neurological Disorders and Stroke. He coordinated the European FP7 large-scale collaborative project EpimiRNA (2013 - 2018) and co-organised the international conferences EpiXchange I and II which brought together Europe’s major epilepsy research projects and which is now supported as a flagship “Cluster” by the European Brain Research Area (EBRA). In 2017, he became Director of FutureNeuro, a €13Mio Science Foundation Ireland Research Centre and the first to be hosted by RCSI, focused on chronic and rare neurological diseases. The Centre is an industry-academia partnership model working to translate findings for patient benefit and includes world-leading investigators in the areas of clinical neurology, genetics, materials science and eHealth based at RCSI, TCD, DCU, UCD, NUI Galway, WIT and UCC.
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FutureNeuro: David Henshall
RCSI: David Henshall
Twitter: Prof_DCHenshall
LinkedIn: david-henshall
Publications: ResearchGate
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