6th Dianalund International Conference on Epilepsy - Overlapping Clinical Phenotypes in Monogenic Epilepsies; Common Molecular Pathways? - Elena Gardella, Rikke Møller, Guido Rubboli, Danish Epilepsy Center, Denmark
Hear about the one-of-a-kind 6th Dianalund International Conference on Epilepsy in May 2024 titled “Overlapping Clinical Phenotypes in Monogenic Epilepsies; Common Molecular Pathways?” - led by genetic clinicians and researchers Elena Gardella, Rikke Møller, and Guido Rubboli.
If you have any questions regarding the conference, registration or what to do if you wish to share a room with a spouse or partner, please don't hesitate to contact us at: dice@filadelfia.dk.
Reported by Torie Robinson | Edited and produced by Carrot Cruncher Media.
Podcast
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Amongst many genetic epilepsies and epileptic encephalopathies, the phenotypic spectrum can be broad (even in patients with identical genetic alterations) and genetic modifiers are typically implicated. Despite their different genetic etiologies, patients can have seemingly similar clinical presentations. For example, SCN1A-related disorders can clinically overlap with other genetic diseases such as those which are GABAA-receptor-related. Then there are various comorbidities – for instance, movement disorders – which can also have features which overlap with those of other conditions. It has been suggested that the comorbidities of distinct phenotypes may reflect an overlap of both the causative genes and the involvement of similar molecular processes for these disorders. It is clear that the study paradigms required to successfully address these questions are lacking and therefore require further research.
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We shall review current knowledge on the phenotypic expressions, their overlapping features, and the genotype-phenotype correlations of some epileptic disorders and epileptic encephalopathies. With an aim to guide the discovery and development of effective targeted treatments, we shall discuss possible underlying and shared pathophysiological mechanisms and molecular substrates and then present both the emerging concepts in the field of precision medicine and the yields of the most advanced research strategies. The conference will conclude with evidence and case presentations from the audience which, based on the understanding of underlying genetic anomalies, support the role of novel treatments.
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Venue: Comwell Køge Strand, Strandvejen 111, 4600 Køge (Denmark).
Comwell Køge Strand is located about 45 km from Copenhagen. Køge can be reached by train from fx Copenhagen Airport. The local train station is a 20 minut walk from the venue, it is also possible transfer from the train station via bus which takes about 10 minutes. If you come by car highway E47 and E20 connects Køge to the rest of Denmark.
If you need to make transfer arrangements from fx CPH airport or Copenhagen Central Station you can plan it here: Rejseplanen
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Rooms are available for the participants at Comwell Køge strand and can be included in the registration.
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€ 500: Full meeting incl. conference dinner (2/5-2024), 2 nights (1-3/5-2024) welcome reception (1/5-2024)
€ 400: Full meeting incl. conference dinner (2/5-2024), 1 night (2-3/5-2024)
€ 300: Full meeting incl. conference dinner (2/5-2024)
€ 100: One day registration
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If you have any questions regarding the conference, registration or what to do if you wish to share a room with a spouse or partner, please don't hesitate to contact us at: dice@filadelfia.dk